United States securities and exchange commission logo March 23, 2022 Anthony Fernando President and Chief Executive Officer Asensus Surgical, Inc. 1 TW Alexander Drive, Suite 160 Durham, NC 27703 Re: Asensus Surgical, Inc. Registration Statement on Form S-3 Filed March 18, 2022 File No. 333-263711 Dear Mr. Fernando: This is to advise you that we have not reviewed and will not review your registration statement. Please refer to Rules 460 and 461 regarding requests for acceleration. We remind you that the company and its management are responsible for the accuracy and adequacy of their disclosures, notwithstanding any review, comments, action or absence of action by the staff. Please contact Alan Campbell at 202-551-4224 with any questions. Sincerely, Division of Corporation Finance Office of Life Sciences cc: Mary J. Mullany, Esquire